SibutraGold® 15mg / 30 tablets
DecaGold® has both androgenic and anabolic properties when administered parentally. Nandrolone decanoate is gradually released from the intramuscular depot and subsequently hydrolyzed into Nandrolone.
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GENERIC NAME
hydrochloride sibutramine
PROPRIETARY NAME
SibutraGold®
DOSAGE FORM
15mg/ 30 tablets – oral
COMPOSITION
15 mg Capsule
Each tablet contains hydrochloride sibutramine: 15mg.
PHARMACOLOGICAL CLASSIFICATION
Anabolic Steroids
PHARMACOKINETIC PROPERTIES
Sibutramine is well absorbed and undergoes extensive first pass metabolism. Maximum plasma levels are reached 1.2 hours after a single oral dose of 20 mg and the half-life of the parent compound is 1.1 hours. The pharmacologically active metabolites 1 and 2 reach Tmax at 3
hours, with elimination half-lives of 14 and 16 hours, respectively. Linear kinetics over the dose range 10 to 30 mg without any change, has been demonstrated dose-related, the elimination half-lives and increased in proportion to dose, plasma concentrations. Under repeated doses, equilibrium concentrations of the metabolites 1 and 2 are achieved in four days with an accumulation of approximately twice. In obese subjects, the pharmacokinetics of sibutramine and its metabolites are similar to those in subjects with normal weight, there is no evidence of
a significant difference in pharmacokinetics in men and women. The pharmacokinetic profile observed in elderly subjects was similar to that seen in younger people. The lead content to proteins plasma of sibutramine and its metabolites 1 and 2 is 97%, 94% and 94%, respectively.
INDICATIONS
SibutraGold® is indicated for the treatment of obesity when weight loss is clinically indicated; should be used in conjunction with diet and exercise, as part of a weight management program, when only the diet and exercise prove to be inefficient.